2-(((9H-fluoren-9-yl)Methoxy)carbonylaMino)-2-(thiophen-3-yl)acetic acid
Fmoc-L-2-(3-Thienyl)-glycine
CAS:
Molecular Formula: C21H17NO4S
2-(((9H-fluoren-9-yl)Methoxy)carbonylaMino)-2-(thiophen-3-yl)acetic acid - Names and Identifiers
2-(((9H-fluoren-9-yl)Methoxy)carbonylaMino)-2-(thiophen-3-yl)acetic acid - Physico-chemical Properties
| Molecular Formula | C21H17NO4S |
| Molar Mass | 379.43 |
2-(((9H-fluoren-9-yl)Methoxy)carbonylaMino)-2-(thiophen-3-yl)acetic acid - Introduction
Fmoc-L-2-(3-Thienyl)-glycine is an organic compound with the following properties:
1. Appearance: white solid
2. molecular formula: C26H21NO4S
3. molecular weight: 439.51
4. melting point: 126-129 ℃
Fmoc-L-2-(3-Thienyl)-glycine are mainly used as reagents and intermediates in the biomedical field. It can be used to synthesize N-alpha protecting groups and C- alpha functional group modifications in the chemical synthesis of polypeptides and proteins. In addition, it can be used for research in chemical biology and drug development.
The preparation of Fmoc-L-2-(3-Thienyl)-glycine is generally achieved by chemical synthesis of amino acid. First, a substitution reaction is carried out on the thiophene ring, which is coupled to the α-carboxyl group to form a thiophene-substituted amino acid. Then, the target product was synthesized by protecting the amino group with an Fmoc protecting group.
Regarding safety information, Fmoc-L-2-(3-Thienyl)-glycine is an organic compound with certain toxicity. Correct experimental operation and personal protective measures should be followed during handling. Direct contact with skin and eyes should be avoided and it is ensured that the operation is carried out in a well-ventilated environment. During use, care should be taken to avoid inhaling its dust and gas. If exposed or inhaled, seek medical advice immediately.
1. Appearance: white solid
2. molecular formula: C26H21NO4S
3. molecular weight: 439.51
4. melting point: 126-129 ℃
Fmoc-L-2-(3-Thienyl)-glycine are mainly used as reagents and intermediates in the biomedical field. It can be used to synthesize N-alpha protecting groups and C- alpha functional group modifications in the chemical synthesis of polypeptides and proteins. In addition, it can be used for research in chemical biology and drug development.
The preparation of Fmoc-L-2-(3-Thienyl)-glycine is generally achieved by chemical synthesis of amino acid. First, a substitution reaction is carried out on the thiophene ring, which is coupled to the α-carboxyl group to form a thiophene-substituted amino acid. Then, the target product was synthesized by protecting the amino group with an Fmoc protecting group.
Regarding safety information, Fmoc-L-2-(3-Thienyl)-glycine is an organic compound with certain toxicity. Correct experimental operation and personal protective measures should be followed during handling. Direct contact with skin and eyes should be avoided and it is ensured that the operation is carried out in a well-ventilated environment. During use, care should be taken to avoid inhaling its dust and gas. If exposed or inhaled, seek medical advice immediately.
Last Update：2024-04-09 21:01:54
